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    Chair of Microbiology

    Chair of Microbiology

    In the focus of research at the Chair of Microbiology are pathogenicity mechanisms of different microorganisms such as Neisseria gonorrhoeae, Chlamydia trachomatis, Bordetella pertussis and Staphylococcus aureus.

    Host-pathogen interactions, pathogen-induced host cell apoptosis as well as the interface of infection and cancer are of peticular interest.

    Follow this link to find out more about our research.

     


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    Microbe of the year: Halobacterium salinarum

    Neueste Publikationen

    • Kozjak-Pavlovic V, Chowdhury SR, Rudel T. Fragment and Conquer. Cell Host Microbe. 2017 Sep 13;22(3):255-257. doi: 10.1016/j.chom.2017.08.014. PMID: 28910630
    • Eisenreich W, Rudel T, Heesemann J, Goebel W. To Eat and to Be Eaten: Mutual Metabolic Adaptations of Immune Cells and Intracellular Bacterial Pathogens upon Infection. Front Cell Infect Microbiol. 2017 Jul 13;7:316. doi: 10.3389/fcimb.2017.00316. eCollection 2017. Review.
    • Chowdhury SR, Rudel T. Chlamydia and mitochondria - an unfragmented relationship. Microb Cell. 2017 Jun 14;4(7):233-235. doi: 10.15698/mic2017.07.582.
    • Tanwer P, Bauer S, Heinrichs E, Panda G, Saluja D, Rudel T, Beier D. Post-transcriptional regulation of target genes by the sRNA FnrS in Neisseria gonorrhoeae. Microbiology. 2017 Jul;163(7):1081-1092. doi: 10.1099/mic.0.000484.
    • Fischer A, Harrison KS, Ramirez Y, Auer D, Chowdhury SR, Prusty BK, Sauer F, Dimond Z, Kisker C, Scott Hefty P, Rudel T. Chlamydia trachomatis-containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to interfere with host defense. Elife. 2017 Mar 28 e21465. doi: 10.7554/eLife.21465. PMID: 28347402
    • Gupta N, ..., Herweg JA, Fischer A, ..., Rudel T, Vacus J, Loiseau PM, Davey RA, Oswald E, Cintrat JC, Barbier J, Gillet D. Inhibitors of retrograde trafficking active against ricin and Shiga toxins also protect cells from several viruses, Leishmania and Chlamydiales. Chem Biol Interact. 2017 Apr 1;267:96-103 doi: 10.1016/j.cbi.2016.10.005 PMID: 27712998

    • Chowdhury SR, Reimer A, Sharan M, Kozjak-Pavlovic V, Eulalio A, Prusty BK, Fraunholz M, Karunakaran K, Rudel T. Chlamydia preserves the mitochondrial network necessary for replication via microRNA-dependent inhibition of fission. J Cell Biol. 2017 Mar 22. pii: jcb.201608063. doi: 10.1083/jcb.201608063 PMID: 28330939

    • Mehlitz A, Eylert E, Huber C, Lindner B, Vollmuth N, Karunakaran K, Goebel W, Eisenreich W, Rudel T. Metabolic adaptation of Chlamydia trachomatis to mammalian host cells. Mol Microbiol. 2017 Mar 103(6):1004-1019. doi: 10.1111/mmi.13603 PMID: 27997721

    • Prusty BK, Gulve N, Rasa S, Murovska M, Hernandez PC, Ablashi DV. Possible chromosomal and germline integration of human herpesvirus 7. J Gen Virol. 2017 Feb 98(2):266-274. doi: 10.1099/jgv.0.000692 PMID: 28284243

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